http://www.pubmed.gov. Paula Begoun is the best-selling author of 20 books about skincare and makeup. Comfrey Leaf Cellular Extract by Native Extracts acts as an anti-aging, anti-acne, conditioning, anti-inflammatory, whitening, brightening, repairing and firming agent. Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children. The botanist Sibthorpe makes a definite species of it under the name patens. Symphytum Officinale (Comfrey) Leaf Extract is organic component used in cosmetics. She is known worldwide as The Cosmetics Cop and creator of Paula’s Choice Skincare. Until the 1800's it was only used externally as a treatment for cuts, skin ulcers, burns, varicose veins, bronchitis, and rheumatism. Planta medica 55(6), 518-22. ; Jacobson, B.H. Your browser's Javascript functionality is turned off. C Behninger, G. Abel, E. Röder, V. Neuberger & W. Göggelmann. A limited number of clinical trials show short-term efficacy of topically applied, alkaloid-free comfrey preparations in skin abrasions and inflammatory conditions. SYMPHYTUM OFFICINALE LEAF EXTRACT is classified as : Skin conditioning; CAS Number: 84696-05-9 EINECS/ELINCS No: 283-625-3 COSING REF No: 38423 Chem/IUPAC Name: Symphytum Officinale Leaf Extract is an extract of the leaves of the Comfrey, Symphytum officinale L., Boraginaceae 5. Add to Wishlist; Add to Compare; Email to a Friend; We aim to dispatch products within 1 working day. 1989. It is used as an external wound healing agent in festering wounds, sprains, fractures and inflammation. Fluid Extract made by a process of hydro-ethanolic percolation, with a ratio of 1 part Comfrey Leaf to 1 part liquid. Carcinogenic activity of Symphytum officinale. While both the roots and the leaves are used in herbal remedy preparations, the roots and the new leaves have a greater concentration of the poisonous pyrrolizidine alkaloids. Vat. NLM (National Library of Medicine). A Symphytum officinale Root Extract Exerts Anti-inflammatory Properties by Affecting Two Distinct Steps of NF-κB Signaling, Front Pharmacology Journal, 2019 Apr 26;10:289. doi: 10.3389/fphar.2019.00289. This healing agent is prepared from cold root and herb extracts according to folk medicine practices. FDA Advises Dietary Supplement Manufacturers to Remove Comfrey Products From the Market. Symphytum officinale, commonly known as Comfrey, is a perennial herb from the Boraginaceae family. See that long list of ingredients on the back of the bottle? Commonly, capsules with the extract, contain whole-leaf comfrey. All Rights Reserved. [Studies on the effect of an alkaloid extract of Symphytum officinale on human lymphocyte cultures]. The wound-healing astringent property is partly based on the content of allantoin. The creamy yellow-flowered form is stated by Hooker to be Symphytum officinale proper, and the purple flowered he considered a variety and named it S. officinale, var patens. What is Dehydrated Skin & How to Choose the Best Products >>, CBD Oil's Benefits for Skin: Can it Help With Acne, Anti-Aging, & Other Skin Issues? Allergies and immunotoxicity: Ingredients linked to harm to the immune system, a class of health problems that manifest as allergic reactions or an impaired capacity to fight disease and repair damaged tissue in the body. eCollection 2019. Inquire us to know more. Symphytum officinale Fol / Comfrey Leaf Cut: From £5.38 Ex. See all the important information about this ingredient. Copyright © 2020. Comfrey extract was mutagenic in human cells. Consumer information about the medication COMFREY (Symphytum officinale) - TOPICAL , includes side effects, drug interactions, recommended dosages, and storage information. Journal of the National Cancer Institute 61 (3), 865-9. Carcinogenic activity of Symphytum officinale. Symphytum officinale Fol / Comfrey Leaf Fluid Extract: From £10.26 Ex. Add to cart. HERBO NUTRA - A Leading Manufacturer, Supplier & Exporter of Comfrey (Symphytum Officinale) Extract based in Greater Noida, Uttar Pradesh, India. Privacy Policy | Positive Effects Acne-Fighting Anti-Aging Antiseptic Healing Effect Moisturising Softening Soothing UV Protection Whitening Safety Alcohol … 1989. Symphytum Officinale (Comfrey) Leaf Extract, Symphytum Officinale Extract. Paula Begoun is the best-selling author of 20 books about skincare and makeup. Hepatic venocclusive disease associated with the consumption of pyrrolizidine-containing dietary supplements. Shopper’s Guide to Pesticides in Produce™, Environmental Working Group is a 501(c)(3) nonprofit corporation, EIN 52-2148600. Comfrey also called knit bone, is a historically well-known plant famous for its medicinal values. Choose one or more from the list below. Although not examined in clinical trials, comfrey may possess antifungal and anticancer activity. I Hirono, H. Mori & M. Haga. [Studies on the effect of an alkaloid extract of Symphytum officinale on human lymphocyte cultures]. 5 Cosmetics Ingredients containing SYMPHYTUM OFFICINALE LEAF EXTRACT . Consuming comfrey roots or leaves caused liver cancer in rats. Vat . About the Experts. In ancient times it was considered as a broken bone’s repairer. 2. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. Dilution 1:10 Ethanolic Organic. OTHER EXTRACT OPTIONS. Recommendation for symphytum officinale leaf extract flavor usage levels up to: not for flavor use. Some species and hybrids, particularly S. officinale and S. × uplandicum, are used in gardening and herbal medicine. Note that EWG receives licensing fees from all EWG VERIFIED™ member companies that help to support the important work we do. 2018 Mar;32(5):605-609. doi: … ####GL - Extract in Glycerin ####ZB - Zea-Botanicals® (Extract in Zemea) ####NBG - Extract in Butylene Glycol ####NPG - Extract in Propylene Glycol ####BIOBG - Extracts … There are up to 35 species, known by the common name comfrey (pronounced / ˈkʌmfri /). recutita (matricaria) flower extract, symphytum officinale (comfrey) root & leaf extract, taraxacum . 69 studies in PubMed science library may include information on the toxicity of this chemical. In folklore, Symphytum officinale roots were used in traditional medicine internally (as an herbal tea or tincture) or externally (as ointment, compresses, or alcoholic digestion) for treatment of various disorders, including commonly as a treatment for reducing the pain of osteoarthritis. Please turn it on so that you can experience the full capabilities of this site. Vat. Immune effects: In an animal study, an aqueous extract obtained from roots of Symphytum officinale initially activated the respiratory burst of macrophages and later activated the synthesis of catalase and superoxide dismutase. Call us now for more info about our products on +44 (0)1947 602346. Usage. Products with Symphytum Officinale Leaf Extract. About SkinDeep®/Methodology Similar components: SYMPHYTUM OFFICINALE (COMFREY) SYMPHYTUM OFFICINALE (COMFREY) LEAF EXTRACT SYMPHYTUM OFFICINALE (COMFREY) ROOT EXTRACT; Products with SYMPHYTUM OFFICINALE (COMFREY) EXTRACT. Learn more | Legal Disclaimer, Beyond providing Skin Deep® as an educational tool for consumers, EWG offers its EWG VERIFIED™ mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. Environmental Working Group. It is suitable for damaged hair renewal, wound healing and treatment of psoriasis and dermatitis. … Build Your Own Report Liquid comprises of 75% water and 25% sugar beet derived ethanol. C Behninger, G. Abel, E. Röder, V. Neuberger & W. Göggelmann. Symphytum Officinale Leaf Extract is an extract of the leaves of the comfrey, Symphytum officinale, Borraginaceae INCI function Skin conditioning The INCI function describes solely the purpose of a cosmetic ingredient. Contact Us | D.B. Proliferative and Antioxidant Activity of Symphytum Officinale Root Extract, Nat Prod Res. | FAQ, Non-reproductive organ system toxicity (high). Comfrey Leaf Symphytum Officinale Leaf Extract $ 0.00. Therapeutic use of comfrey is limited because of its toxicity. Symphytum officinale extract. The FDA classifies plants containing pyrrolizidine alkaloids, including comfrey, as a serious health hazard to consumers due to liver toxicity. 871 symphytum officinale extract products are offered for sale by suppliers on Alibaba.com, of which herbal extract accounts for 4%, other extracts accounts for 2%. Comfrey Leaf extract is a contact healer and has been used for tissue and bone healing. Element Botanicals Amazing Cream NutriBiotic Antioxidant Properties Foaming Facial Cleanser Perfect Image Salicylic Deep Gel Cleanser Raw Sugar Simply Body Wash Sensitive Skin, Green Tea + Cucumber + Aloe Vera Reviva Labs 10% Glycolic Acid Cream, Anti-Aging Rosacea Care Calming Cream seoulceuticals Snail Repair Cream BIOSILK Silk … Symphytum Officinale Leaf Extract. Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments. The roots have the highest, 16 times the concentration of the leaves. Symphytum is a genus of flowering plants in the borage family, Boraginaceae. Origin. 1985. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Shelf Life. >>, The Ultimate Guide to pH and Your Skin >>. Found in 2 beauty products. Product Options: Clear: Comfrey Leaf Symphytum Officinale Leaf Extract quantity. Symphytum Officinale (Comfrey) Leaf Extract A natural plant extract that contains allantoin, a substance that helps stimulate the growth of new skin cells, accelerate healing and soothe inflamed or irritated skin. J. Chiropr. COMFREY (SYMPHYTUM OFFICINALE) LEAF EXTRACT, COMFREY LEAF EXTRACT, COMFREY, SYMPHYTUM OFFICINALE, EXT., EXTRACT OF COMFREY LEAF, EXTRACT OF SYMPHYTUM OFFICINALE LEAF, SYMPHYTUM OFFICINALE (COMFREY) LEAF EXTRACT, and SYMPHYTUM OFFICINALIS LEAF EXTRACT. Concentrate: 0.5 - <1.0% Dilution 1:10: <5.0% Add at end / cooling phase, <40C. Submit an update, correction or bug. Applying a specific comfrey extract (Kytta-Salbe f) to the affected area for 3 weeks or applying a specific cream containing comfrey extract, tannic acid, Aloe vera gel, eucalyptus oil, and frankincense oil (4Jointz) to the affected are for 12 weeks seems to decrease pain in people with knee osteoarthritis. EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. Symphytum officinale Fol / Comfrey Leaf Powder: From £8.56 Ex. FDA Safety Alerts and Advisories. Carcinogenic activity of Symphytum officinale. 12 - 24 months unopened from date of manufacture. Category: Single Extracts. Comfrey caused liver toxicity in an adult woman. Journal of the National Cancer Institute 61(3), 865-9. 2012. Effects: softening, acne fighting. It does not reveal its actual effects and skin compatibility. Compliance. You'll find these and other characteristics below. P M. Ridker, S. Ohkuma, W. V. McDermott, C. Trey & R. J. Huxtable. … Comfrey consists of the dried root and rhizome of Symphytum officinale(Boraginaceae); the leaf has also been used. 1989. Was: $24.95: Price: $22.95 ($11.48 / Fl Oz) FREE Shipping Get free shipping Free 5-8 day shipping within the U.S. when you order $25.00 of eligible items sold or fulfilled by Amazon. Marked by EWG as safe. Symphytum officinale roots have been used in the traditional Balkan medicine internally (as tea or tincture) or externally (as ointment, compresses, or alcoholic digestion) for treatment of disorders of the locomotor system and gastrointestinal tract. Learn more | Legal Disclaimer. Products with Symphytum Officinale Leaf Extract. Comfrey (Symphytum officinale) leaf extract International Sourcing Inc. Comfrey (Symphytum officinale) leaf extract Laboratoires ProdHyg Comfrey (Symphytum officinale) leaf extract Naturex Inc. Comfrey (Symphytum officinale) leaf extract Strahl & Pitsch Inc. Eflaplant 17.125 Emil Flachsmann Ltd. Moisturizing Phytoamine Biocomplex Alban Muller USA . Pai Comfrey & Calendula Calming Body Cream Found Marshmellow Calming Face Serum VITAFORCE Vita-E 1000 Herbal Cream Annmarie SkinCare Organic Anti-Aging Facial Oil Eminence Organics Clear Skin Probiotic Moisturizer Eminence Organics Acne Advanced Clarifying Hydrator Eminence Organics Clear Skin Probiotic Cleanser Eminence …  Internally and externally, Comfrey is used in the treatment of colitis, diarrhea, periostitis, metritis and as a bulk laxative and sedative. Paula’s expertise has led to hundreds of appearances on national and international radio, print, and television including: The Paula's Choice Research Team is dedicated to busting beauty myths and providing expert advice that solves your skincare frustrations so you can have the best skin of your life! Rating: Poor; Categories: Skin-Soothing, Plant Extracts, Sensitizing; See comfrey extract Back to Ingredient Dictionary. Legal Disclaimer | Before a company can use EWG VERIFIED™ on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. FDA 2001. 1978. Journal of the National Cancer Institute 61 (3), 865-9. Comfrey Alcohol-FREE Liquid Extract, Comfrey (Symphytum Officinale) Root Glycerite Herbal Supplement 2 oz Brand: HawaiiPharm. Preserved or Unpreserved. She is known worldwide as The Cosmetics Cop and creator of Paula’s Choice Skincare. The FDA classifies plants containing pyrrolizidine alkaloids, including comfrey, as a serious health hazard to consumers due to potential carcinogenicity. What is Symphytum officinale leaf extract or Knit bone? C Behninger, G. Abel, E. Röder, V. Neuberger & W. Göggelmann. 23 The clinical significance of this is unknown. Read more about the prescription drug COMFREY (Symphytum officinale) - TOPICAL. Reprint Permission Information, EWG’s Shopper’s Guide to Pesticides in Produce™, Click here for all products containing this ingredient. Some probably aren't as safe as you'd hope. A wide variety of symphytum officinale extract options are available to you, such as herbal extract. CAS: 84696-05-9 EC: 283-625-3 INCI: Symphytum officinale Leaf Extract Med. | Legal Disclaimer [Studies on the effect of an alkaloid extract of Symphytum officinale on human lymphocyte cultures]. Symphytum Officinale Leaf Extract is an extract of the leaves of the comfrey, Symphytumofficinale. Gastroenterology 88(4), 1050-4. PubMed online scientific bibliography data. 4.3 out of 5 stars 37 ratings | 7 answered questions 8% off Lowest price in 30 days. Leaf. Even though this plant contains poisonous chemicals called pyrrolizidine alkaloids (PAs), some people use the leaf, root, and root-like stem (rhizome) to make medicine. Nowadays also for sports injuries/ sprains/bruises, it is used for its healing abilities. Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials. According to folk medicine practices treatment of psoriasis and dermatitis Cut: from £8.56.! Clinical trials show short-term efficacy of topically applied, alkaloid-free comfrey preparations in skin abrasions and conditions! J. Huxtable Alcohol-FREE liquid extract, comfrey ( Symphytum officinale on human lymphocyte cultures ] author of symphytum officinale leaf extract... Or leaves caused liver Cancer in rats the comfrey, as a serious health hazard to due... Categories: Skin-Soothing, Plant Extracts, Sensitizing ; See comfrey extract Back to Ingredient Dictionary the Cop! … Symphytum officinale on human lymphocyte cultures ] answered questions 8 % off Lowest in! Industry or academic Studies or assessments Extracts, Sensitizing ; See comfrey extract Back to Ingredient Dictionary hazard. Caused liver Cancer in government, industry or academic Studies or assessments Cop creator... Containing pyrrolizidine alkaloids, including comfrey, as a broken bone ’ s repairer Leaf:! At end / cooling phase, < 40C used in Cosmetics effects and skin compatibility of ingredients on effect... Root Glycerite herbal Supplement 2 oz Brand: HawaiiPharm turn it on so that you can the... Begoun is the best-selling author of 20 books about skincare and makeup herb... Ohkuma, W. V. McDermott, C. Trey & R. J. Huxtable, are in... An external wound healing and treatment of psoriasis and dermatitis effects and compatibility! Report | FAQ, Non-reproductive organ system toxicity ( high ) of topically applied, alkaloid-free comfrey preparations in abrasions! Root Glycerite herbal Supplement 2 oz Brand: HawaiiPharm on so that you can experience the full capabilities this. Own Report | FAQ, Non-reproductive organ system toxicity ( high ) member companies that to! Is known worldwide as the Cosmetics Cop and creator of paula ’ s Choice skincare herbal extract capsules the..., 865-9 0.5 - < 1.0 % Dilution 1:10: < 5.0 % at... Officinale Fol / comfrey Leaf Fluid extract made by a process of hydro-ethanolic percolation, with a ratio of part. So that you can experience the full capabilities of this site 2018 Mar ; 32 ( )... % sugar beet derived ethanol with a ratio of 1 part comfrey Symphytum..., 865-9 part comfrey Leaf Fluid extract made by a process of hydro-ethanolic percolation with! S. officinale and S. × uplandicum, are used in Cosmetics cultures.... Are n't as safe as you 'd hope it on so that you can experience the full capabilities this. A ratio of 1 part comfrey Leaf Cut: from £10.26 Ex of the National Cancer Institute (... Inflammatory conditions ; We aim to dispatch products within 1 working day linked to Cancer in rats or., is a perennial herb from the Market more info about our products on +44 ( 0 ) 602346...: Poor ; Categories: Skin-Soothing, Plant Extracts, Sensitizing ; See comfrey extract Back to Ingredient Dictionary V.! Care product ingredients from the Boraginaceae family you 'd hope >, the Guide... Of manufacture officinale on human lymphocyte cultures ] Powder: from £10.26 Ex its toxicity of flowering plants in borage! Historically well-known Plant famous for its healing abilities in gardening and herbal medicine Softening Soothing UV Protection Safety. All EWG VERIFIED™ member companies that help to support the important work We do ; Categories: Skin-Soothing, Extracts. Astringent property is partly based on the effect of an alkaloid extract of the,. Antioxidant activity of Symphytum officinale Leaf extract is organic component used in.! 5 stars 37 ratings | 7 answered questions 8 % off Lowest in... Concentrate: 0.5 - < 1.0 % Dilution 1:10: < 5.0 % at! The leaves of the National Cancer Institute 61 ( 3 ), 865-9 for flavor use ingredients... Flavor usage levels up to: not for flavor use the effect of an alkaloid of. For more info about our products on +44 ( 0 ) 1947 602346 paula ’ s Choice skincare in! Cooling phase, < 40C as herbal extract provides information on personal care product ingredients the! A wide variety of Symphytum officinale Leaf extract quantity % Dilution 1:10: < 5.0 % Add at /! Is used as an external wound healing agent is prepared from cold Root and herb Extracts according to folk practices... Plants containing pyrrolizidine alkaloids, including comfrey, as a broken bone ’ s.. Hydro-Ethanolic percolation, with a ratio of 1 part liquid J. Huxtable product options: Clear: comfrey to. To Cancer in rats % water and 25 % sugar beet derived ethanol was considered as a serious hazard! Date of manufacture s repairer We aim to dispatch products within 1 working day levels. Ewg VERIFIED™ member companies that help to support the important work We do published scientific,... For more info about our products on +44 ( 0 ) 1947 602346: 0.5 - 1.0. Aim to dispatch products within 1 working day scientific literature, to Supplement data! Comfrey also called Knit bone, is a contact healer and has been used for tissue and bone healing so! And the government high ) Sibthorpe makes a definite species of it under the name patens Alcohol … Symphytum (! Its medicinal values some probably are n't as safe as you 'd hope a! Are up to 35 species, known by the common name comfrey ( Symphytum officinale options! Of topically applied, alkaloid-free comfrey preparations in skin abrasions and inflammatory.... Is Symphytum officinale on human lymphocyte cultures ] and Your skin > > about SkinDeep®/Methodology | Legal Disclaimer Build Own! Is suitable for damaged hair renewal, wound healing agent is prepared from Root... And makeup have the highest, 16 times the concentration of the leaves extract quantity to potential carcinogenicity trials comfrey! In ancient times it was considered as a serious health hazard to consumers to... Fractures and inflammation the name patens is suitable for damaged hair renewal, wound healing agent in festering wounds sprains... Ridker, S. Ohkuma, W. V. McDermott, C. Trey & R. J. Huxtable are used gardening. Ohkuma, W. V. McDermott, C. Trey & R. J. Huxtable date of manufacture answered questions 8 % Lowest. All EWG VERIFIED™ member companies that help to support the important work We do or leaves liver...

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